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Adding drug dose calculator (Atorvastatin), GRACE(Discharge) score

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This commit is contained in:
saksham vitwekar
2026-04-06 08:59:10 +05:30
parent 4c36ad570c
commit dfe1f52545
9 changed files with 505 additions and 41 deletions
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146
src/app/utils/calculators/Drug Dose Calculator/Adult.ts Normal file
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@@ -0,0 +1,146 @@
import { Calculator, Drug, Input, Interpretation, Values, inputOptions } from "../types"
import { DrugRegistry } from "./drugs/drug_registry"
function generateDrugList():inputOptions[] {
const drugs:inputOptions[] = DrugRegistry.map(e => {
console.log(e.name);
const drug:inputOptions = {
label:e.name,
value:e.id
}
return drug;
});
console.log(drugs);
return drugs;
}
const parameters:Input[] = [
{
id:"drug",
name:"Drug name",
placeholder:"Select the drug by searching its name below",
type:"search",
inputOptions:generateDrugList()
},
{
id:"weight",
name:"Weight",
placeholder:"Enter the weight of the patient",
type:"number"
},
{
id:"ckd",
name:"CKD Stage",
placeholder:"Whether the patient has CKD, if yes, select the stage",
type:"select",
inputOptions:[
{
label:"None",
value:"none"
},
{
label:"CKD stage 3a",
value:"3A"
},
{
label:"CKD Stage 3B",
value:"3B"
},
{
label:"CKD Stage 4",
value:"4"
},
{
label:"CKD Stage 5 / ESRD",
value:"5"
}
]
},
{
id:"cld",
name:"CLD Stage (Child Pugh)",
placeholder:"Whether the patient has CLD, if yes, select the Child Pugh Stage",
type:"select",
inputOptions:[
{
label:"None",
value:"none"
},
{
label:"Child Pugh A",
value:"A"
},
{
label:"Child Pugh B",
value:"B"
},
{
label:"Child Pugh C",
value:"C"
}
]
}
]
export const Adult_Drug_Calculator:Calculator = {
id:"adult_drug_calculator",
name:"Adult Dose Calculator",
desc:"Adult Dose Calculator can be used to calculate the drug dosing of different dose which also accounts for different comorbidities like CKD and CLD",
inputs:parameters,
calc_func:(values : Values) : string | number => {
const drugID = values.drug as string;
const weight = values.weight as number;
const ckd = values.ckd as "none" | "3A" | "3B" | "4" | "5";
const cld = values.cld as "none" | "A" | "B" | "C";
const drug = DrugRegistry.find(e => e.id === drugID);
if(drug){
if(typeof drug.cld_dosing !== "undefined" && typeof drug.ckd_dosing !== "undefined" && ckd !== "none" && cld == "none"){
const dosingObj = drug.cld_dosing.find(e => e.stage === cld);
if(drug.isWeightBased){
return `${Math.floor(dosingObj?.dosing * weight)} ${drug.unit}`;
}else{
return `${Math.floor(dosingObj?.dosing)} ${drug.unit}` || 0;
}
}else if(typeof drug.cld_dosing !== "undefined" && cld !== "none"){
const dosingObj = drug.cld_dosing.find(e => e.stage === cld);
if(drug.isWeightBased){
return `${Math.floor(dosingObj?.dosing * weight)} ${drug.unit}`;
}else{
return `${Math.floor(dosingObj?.dosing)} ${drug.unit}` || 0;
}
}else if(typeof drug.ckd_dosing !== "undefined" && ckd !== "none"){
const dosingObj = drug.ckd_dosing.find(e => e.stage === ckd);
if(drug.isWeightBased){
return `${Math.floor(dosingObj?.dosing * weight)} ${drug.unit}`;
}else{
return `${Math.floor(dosingObj?.dosing)} ${drug.unit}` || 0;
}
}else{
if(drug.isWeightBased){
return `${Math.floor(drug.adult_dosing * weight)} ${drug.unit}`;
}else{
return `${drug.adult_dosing} ${drug.unit}`;
}
}
}else{
return -1;
}
},
interpret_func:(dosing:number | string):Interpretation => {
if(dosing === 0){
return {
level:"severe",
message:"Drug is to be avoided in patient"
}
}else if(dosing === -1){
return {
level:"none",
message:"Drug not found"
}
}else{
return {
level:"low",
message:`Calculated dosing for the drug is ${dosing ? dosing : null}`
}
}
}
}

24
src/app/utils/calculators/Drug Dose Calculator/drugs/Cardiology/atorvastatin.ts Normal file
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@@ -0,0 +1,24 @@
import { Drug } from "../../../types";
export const Atorvastatin:Drug = {
id:"atorvastatin",
name:"Atorvastatin",
adult_dosing:"10mg to 20mg",
pediatric_dosing:"10mg to 20mg",
isWeightBased:false,
max_dose:"80mg",
max_dose_pediatric:"20mg",
unit:"mg",
cld_dosing:[
{
stage:"B",
to_be_given:true,
dosing:"5-10mg OD",
max_dose:"20mg"
},
{
stage:"C",
to_be_given:false
}
]
};

23
src/app/utils/calculators/Drug Dose Calculator/drugs/Cardiology/metoprolol.ts Normal file
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@@ -0,0 +1,23 @@
import { Drug } from "../../../types";
export const metoprolol:Drug = {
id:"metoprolol",
name:"Metoprolol",
adult_dosing:1.5,
max_dose:"200mg",
isWeightBased:true,
unit:"mg",
pediatric_dosing:0.5,
cld_dosing:[
{
stage:"B",
to_be_given:true,
dosing:0.5
},
{
stage:"C",
to_be_given:true,
dosing:0.25
}
]
}

8
src/app/utils/calculators/Drug Dose Calculator/drugs/drug_registry.ts Normal file
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@@ -0,0 +1,8 @@
import { Drugs } from "../../types";
import { Atorvastatin } from "./Cardiology/atorvastatin";
import { metoprolol } from "./Cardiology/metoprolol";
export const DrugRegistry:Drugs = [
Atorvastatin,
metoprolol
];

216
src/app/utils/calculators/General Cardiology/GRACE_Discharge.ts Normal file
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@@ -0,0 +1,216 @@
import { Calculator, Input, Interpretation, Values } from "../types";
const parameters:Input[] = [
{
id:"age",
name:"Age",
placeholder:"Enter the age",
type:"number",
required:true
},
{
id:"hr",
name:"Heart Rate",
placeholder:"Enter the Heart Rate",
type:"number",
required:true,
defaultUnit:"beats/minute"
},
{
id:"sbp",
name:"Systolic Blood Pressure",
placeholder:"Enter the Systolic Blood Pressure",
type:"number",
required:true,
defaultUnit:"mmHg"
},
{
id:"cret",
name:"Serum Creatinine",
placeholder:"Enter the serum creatinine",
type:"number",
required:true,
defaultUnit:"mg/dL"
},
{
id:"cardiacmarkers",
name:"Elevated Cardiac Markers",
placeholder:"Whether the patient had elevated cardiac markers",
type:"checkbox",
required:true
},
{
id:"deviation",
name:"ST segment depression",
placeholder:"Whether the patient had ST segment depression",
type:"checkbox",
required:true
},
{
id:"chf",
name:"Congestive Heart Failure",
placeholder:"Whether the patient has a history of Congestive Heart Failure",
type:"checkbox"
},
{
id:"pci",
name:"Percutaneous Coronary Intervention",
placeholder:"Whether the patient had a PCI during hospital stay",
type:"checkbox"
},
{
id:"mi",
name:"History of Myocardial Infarction",
placeholder:"Whether the patient has a history of Myocardial Infarction",
type:"checkbox"
}
]
export const GRACE_Discharge : Calculator = {
id:"grace_discharge",
name:"GRACE 1.0 (Discharge)",
desc:"The GRACE (Global Registry for Acut Coronary Events) Score is a clinical tool to estimate the risk of death or myocardial infarction (MI) for 6 weeks in patients after discharge who have suffered Acute Coronary Syndrone (ACS)",
inputs:parameters,
calc_func:(values: Values):number => {
const age = values.age as number;
const hr = values.hr as number;
const sbp = values.sbp as number;
const cret = values.cret as number;
const chf = values.chf as boolean;
const pci = values.pci as boolean;
const deviation = values.deviation as boolean;
const mi = values.mi as boolean;
const cardiacmarkers = values.cardiacmarkers as boolean;
var score = 0;
if(age < 40) score = score + 0;
else if(age >=40 && age < 50) score = score + 18;
else if(age >= 50 && age < 60) score = score + 36;
else if(age >= 60 && age < 70) score = score + 55;
else if(age >= 70 && age < 80) score = score + 73
else if(age >= 80 && age < 90) score = score + 91;
else score = score + 100;
if (hr < 50) score += 0;
else if (hr <= 69) score += 3;
else if (hr <= 89) score += 9;
else if (hr <= 109) score += 14;
else if (hr <= 149) score += 23;
else if (hr <= 199) score += 35;
else score += 43;
if (sbp < 80) score += 24;
else if (sbp <= 99) score += 22;
else if (sbp <= 119) score += 18;
else if (sbp <= 139) score += 14;
else if (sbp <= 159) score += 10;
else if (sbp <= 199) score += 4;
else score += 0;
if (cret <= 0.39) score += 1;
else if (cret <= 0.79) score += 3;
else if (cret <= 1.19) score += 5;
else if (cret <= 1.59) score += 7;
else if (cret <= 1.99) score += 9;
else if (cret <= 3.99) score += 15;
else score += 20;
if (chf) score += 24;
if (deviation) score += 11;
if(pci) score += 14;
if(mi) score += 12;
if(cardiacmarkers) score += 15;
return score;
},
interpret_func:(score : number) : Interpretation => {
if(score <= 60) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 0.2%"
}
if(score <= 70 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 0.3%"
}
if(score <= 80 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 0.4%"
}
if(score <= 90 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 0.6%"
}
if(score <= 100 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 0.8%"
}
if(score <= 110 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 1.1%"
}
if(score <= 120 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 1.6%"
}
if(score <= 130 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 2.1%"
}
if(score <= 140 ) return {
level:"low",
message:"Probability of In Hospital Mortality is less than or equal to 2.9%"
}
if(score <= 150 ) return {
level:"moderate",
message:"Probability of In Hospital Mortality is less than or equal to 3.9%"
}
if(score <= 160 ) return {
level:"moderate",
message:"Probability of In Hospital Mortality is less than or equal to 5.4%"
}
if(score <= 170 ) return {
level:"moderate",
message:"Probability of In Hospital Mortality is less than or equal to 7.3%"
}
if(score <= 180 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 9.8%"
}
if(score <= 190 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 13%"
}
if(score <= 200 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 18%"
}
if(score <= 210 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 23%"
}
if(score <= 220 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 29%"
}
if(score <= 230 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 36%"
}
if(score <= 240 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 44%"
}
if(score < 250 ) return {
level:"severe",
message:"Probability of In Hospital Mortality is less than or equal to 44%"
}
if(score >= 250) return {
level:"severe",
message:"Probability of In Hospital Mortality is more than or equal to 52%"
}
return{
level:"none",
message:"Invalid Value"
}
}
}

14
src/app/utils/calculators/registry.ts
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@@ -9,6 +9,8 @@ import { MELDNa } from "./Utilities/MELDNa";
import { GRACE_Inhosp } from "./Emergency/GRACE_Inhosp";
import { HEART_Score } from "./General Cardiology/HEART_Score";
import { HASBLED } from "./Arrhythmias and Anti-Coagulation/HAS-BLED";
import { GRACE_Discharge } from "./General Cardiology/GRACE_Discharge";
import { Adult_Drug_Calculator } from "./Drug Dose Calculator/Adult";
export const CalculatorRegistry : Record<string, Section> = {
generalCardiology:{
@@ -17,7 +19,17 @@ export const CalculatorRegistry : Record<string, Section> = {
textColor:"#ccc",
svg:"",
calculators:[
MAP
MAP,
GRACE_Discharge
]
},
drugDoseCalculator:{
id:"drugDosing",
displayName:"Drug Dose Calculator",
textColor:"#ccc",
svg:"",
calculators:[
Adult_Drug_Calculator
]
},
arrhythmias:{

28
src/app/utils/calculators/types.ts
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@@ -8,7 +8,7 @@ export interface Calculator {
interpret_func:Function,
customComponent?:React.FC
}
interface inputOptions {
export interface inputOptions {
label:string,
value:string | number ;
}
@@ -52,3 +52,29 @@ export interface pastUsed {
unit: string | undefined
}
export type Values = Record<string, string | number | boolean >;
export interface Drug {
id:string,
name:string,
adult_dosing:number | string,
pediatric_dosing?:number | string,
max_dose: number | string,
max_dose_pediatric?: number | string
isWeightBased:boolean
unit:string,
ckd_dosing?:
{
stage: "none" |"3A" | "3B" | "4" | "ESRD",
to_be_given:boolean
dosing?:number | string,
max_dose?:number | string
}[],
cld_dosing?: {
stage:"none" | "A" | "B" | "C",
to_be_given: boolean,
dosing?: number | string,
max_dose?:number | string
}[]
}
export type Drugs = Drug[];