CockCroft Gault Equation
CockCroft Gault Equation is an equation which is used to calculate the eGFR (Estimated Glomerular Filtration Rate) of a patient
Unit:- mL/min
It takes the following parameters
| Parameter |
Range |
unit |
| Age |
18-95 |
- |
| Serum Creatinine |
0.2 - 20 |
mg/dL |
| weight |
10 - 100 |
kg |
| Gender |
- |
- |
Formula
It uses the following formula to calculate the GFR
GFR = \frac{(140 - Age)}{(72 \times S. Creatinine)} \times 0.85 \text{(if patient is female)}
Interpretation
GFR can be interpreted by using the following table
| Range of GFR |
Stage |
Message |
| more than 90 mL/min |
CKD Stage 1 |
Renal Function is normal |
| 60 - 90 mL/min |
CKD Stage 2 |
Renal Function is slightly reduced |
| 45 - 60 mL/min |
CKD Stage 3A |
Renal Function is moderately reduced |
| 30 - 45 mL/min |
CKD Stage 3B |
Renal Function is significantly reduced |
| 15 - 30 mL/min |
CKD Stage 4 |
Renal Function is largely reduced |
| less than 15 mL/min |
CKD Stage 5 / ESRD |
Renal Function is severely reduced |
Notice:-
This equation of calculating eGFR is not as accurate, other equations like MDRD and CKD-EPI are recommended. Equation is not reliable in the cases of AKI (Acute Kidney Injury). Consultation with a Nephrologist is always recommended. No diagnosis should be made just on the basis of a medical calculator. Other clinical clues are to be taken into account (Urinalysis, UACR(Urine Albumin to Creatinine Ratio) etc.)